From Greensboro
Take I-40 West to exit 212B. Merge onto Greensboro Urban Loop (future 73). Merge onto Bryan Blvd. west. Exit off Bryan Blvd. onto Piedmont Triad International Airport exit.

From Winston-Salem
Take I-40 East or Business 40 East to exit 210. Take exit 210. Turn left onto NC 68 North and drive approximately 2 miles. Take PTIA exit.

From Charlotte, Concord, Salisbury and Lexington
Take I-85 North to US 52 North to exit 87. Take exit 107 A to I-40 East
to exit 210. Turn left onto NC 68 North and drive approximately 2 miles. Take PTIA exit.

From North Wilkesboro and Boone
Take 421 South to I-40 East. Take exit 210. Turn left onto NC 68 North and drive approximately 2 miles. Take PTIA exit.

From Danville, Virginia
Take US 29 South to I-40 West I-40 West to exit 212 B. Merge onto Bryan Blvd. west. Exit off Bryan Blvd. onto Piedmont Triad International Airport exit.

From Roanoke and Martinsville, Virginia
Take US 220 South to NC 68 South. Take PTIA exit.

From Statesville
Take I-40 East to exit 210. Take exit 210. Turn left onto NC 68 North and drive
approximately 2 miles. Take PTIA exit.

From Asheboro
US 220 North to I-40 West, I-40 West to exit 212 B. Merge onto Bryan Blvd. west. Exit off Bryan Blvd. onto Piedmont Triad International Airport exit.

From Elkin
I-77 South to I-40 East. Take exit 210. Turn left onto NC 68 North and drive
approximately 2 miles. Take PTIA exit.

From Raleigh/Durham
I-40 West to exit 212 B. Merge onto Bryan Blvd. west. Exit off Bryan Blvd. onto Piedmont Triad International Airport exit.